アクネ ヴルガリス の 管理: レビュー
Dawn Z Eichenfield1,2, Jessica Sprague1,2, Lawrence F Eichenfield1,2,3
1Department of Dermatology, University of California San Diego School of Medicine, La Jolla.
JAMA
|November 23, 2021
まとめ
アクネ・ヴルガリスは 皮膚に共通する病気で 世界中で何百万人も 罹患しています 有効な治療法は,局所的なレチノイドから軽度の症例まで,口服抗生物質や重度のニキビに対するイソトレチノインのような全身療法まであります.
科学分野:
- 皮膚科
- 炎症性皮膚疾患
背景:
- アクネ・ヴルガリスは,ピロセバセウスユニットに影響を与える一般的な炎症性皮膚疾患です.
- 世界の人口の約9%,特に青少年と若年層に影響します.
- アクネは傷痕や 生活の質の低下や 心理的苦痛につながる可能性があります
研究 の 目的:
- アクネ・ヴルガリスの分類と治療の見直し
- 先進的な治療法を強調する
主な方法:
- 年齢,病変形態,分布,重症度による分類
- レチノイド,ベンゾイル過酸化物,アゼラ酸を含む第一線局所療法に関するレビュー
- 重度のニキビに対する全身療法の評価:経口抗生物質,ホルモン剤,およびイソトレチノイン.
主要な成果:
- トピカル・トレチノインは,病変数を63%減少させました.
- 併用経口避妊薬 (COC) は,炎症性病変の62%の減少を示した.
- 経口抗生物質は炎症的病変を 58% 減少させました
結論:
- 局所薬は,ほとんどのの症例の主要な治療法です.
- 経口抗生物質,ホルモン剤 (COC,スピロノラクトン),およびイソトレチノインを含む全身療法が重症または抵抗性のあるニキビに有効である.
- 治療の選択は,ニキビの重症度,形状,および患者の要因に依存します.
関連する概念動画
Accessory Structures of the Skin: Sebaceous Glands
2.7K
A sebaceous gland is a type of oil gland found almost all over the skin ( except palms and soles) and helps lubricate and waterproof the skin and hair. Most sebaceous glands are associated with hair follicles. They generate and excrete sebum, a mixture of lipids, onto the skin surface, thereby naturally lubricating the dry and dead layer of keratinized cells of the stratum corneum, keeping it pliable.
These glands that produce the oils on the skin and hair are holocrine glands. The mature...
These glands that produce the oils on the skin and hair are holocrine glands. The mature...
2.7K
Asthma: Pathogenesis and Management
815
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
815
Peptic Ulcer Disease IV: Management
163
Medical treatment strategies for peptic ulcers encompass various methods. The primary goal of treatment is to diminish gastric acidity and strengthen mucosal defense mechanisms.
The therapeutic approach involves ensuring adequate rest, implementing drug therapy, promoting smoking cessation, making dietary modifications, and emphasizing long-term follow-up care.
Pharmacological management
The prevailing therapy for peptic ulcers involves a combination of managing the patient's current...
The therapeutic approach involves ensuring adequate rest, implementing drug therapy, promoting smoking cessation, making dietary modifications, and emphasizing long-term follow-up care.
Pharmacological management
The prevailing therapy for peptic ulcers involves a combination of managing the patient's current...
163
Atherosclerosis III: Management
63
Management of atherosclerosis involves an integrated strategy encompassing pharmacological treatment, surgical interventions, lifestyle changes, and nutrition therapy to address the multifactorial nature of the disease.Pharmacological TherapyA cornerstone of atherosclerosis management is the use of pharmacological agents. Statins, such as atorvastatin, are pivotal in inhibiting HMG-CoA reductase, an enzyme that catalyzes an initial step in cholesterol synthesis in the liver. This reduction in...
63
Cystic Fibrosis: Management
240
Cystic fibrosis (CF) is an autosomal recessive disorder that predominantly affects individuals of Northern European descent, occurring at a rate of 1 in 3500. It is caused by a genetic mutation in a gene on chromosome 7, most commonly the ΔF508 mutation, that codes for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. This results in thicker mucus secretions and obstruction pathologies in multiple organs, including the lungs and sinuses.
Sinus disease and chronic...
Sinus disease and chronic...
240
Tonsillitis II: Management
194
This lesson will focus on the different treatment options for managing tonsillitis, which typically depend on the cause and severity.
194


