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Updated: Oct 12, 2025

Quick Fluorescent In Situ Hybridization Protocol for Xist RNA Combined with Immunofluorescence of Histone Modification in X-chromosome Inactivation
12:42

Quick Fluorescent In Situ Hybridization Protocol for Xist RNA Combined with Immunofluorescence of Histone Modification in X-chromosome Inactivation

Published on: November 26, 2014

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Xistは,X染色体全体にサイレンシングを広めるために,局所的なタンパク質グラデーションを核化する

Yolanda Markaki1, Johnny Gan Chong1, Yuying Wang1

  • 1Department of Biological Chemistry, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.

Cell
|November 23, 2021
PubMed
まとめ

長い非コーディングRNAのXistはX染色体を静止する複合体を形成する. これらの複合体は 多くの遺伝子を制御するために タンパク質の群集を利用し 遺伝子の調節と核組織の新しいメカニズムを明らかにします

キーワード:
RNA結合タンパク質X染色体の不活性化シストRNAバイオ分子凝縮物クロマチン組織ヘテロクロマチンマクロ分子ダイナミクス定量的イメージング超高解像度顕微鏡超分子複合体

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