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Updated: Oct 12, 2025

Measurements of Physiological Stress Responses in C. Elegans
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アルデヒドによる転写ストレスが,食欲不良のDNA損傷反応を誘発する

Lee Mulderrig1,2, Juan I Garaycoechea3, Zewen K Tuong4,5

  • 1MRC Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK.

Nature
|November 25, 2021
PubMed
まとめ

内部ホルマルデヒドはDNAに損傷を与え トランスクリプションを阻害し コケイン症候群のような症状を引き起こします GDF15信号を遮断すると,カケキシアが緩和され,病気の病原性における役割が示唆される.

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