種別レベルの哺乳類の進化のタイムライン

Sandra Álvarez-Carretero^1,2, Asif U Tamuri^3,4, Matteo Battini⁵

¹School of Biological and Behavioural Sciences, Queen Mary University of London, London, UK.

Nature

|December 22, 2021

まとめ

新しいベイジアン法では 72の哺乳類のゲノムを分析して種レベルのタイムツリーを作成しますこれは,胎盤哺乳類の進化の議論の余地のある時間スケールを解決し,彼らの起源を白亜紀後期に配置します.

科学分野:

進化生物学
ゲノミクス
コンピュータ生物学

背景:

ハイ・スループット・シーケンシングは系統遺伝子の膨大なデータを生成する.
現在のベイジアンタイムツリー方法は計算的に制限されており,大規模なデータセットの分析を妨げています.
哺乳類の分子時計の分析は矛盾する年齢推定と大きな不確実性をもたらします

研究の目的:

大規模なゲノムデータセットのためのベイジアン分子時計年代測定アプローチを開発する.
72種類の哺乳類のゲノムを使って,4,705種の哺乳類のタイムツリーを推定する.
マクロ進化の仮説を検証するために,多様化の時間推定の精度を向上させる.

主な方法:

新しいベイジアン分子時計の年代測定法を開発した.
4,705種の哺乳類のゲノムから集めたデータです.
哺乳類の全般的な時間軸を推論した.

主要な成果:

多様化時間の推定における不確実性を減らすことが示された.
プラセンタ哺乳類起源の爆発的なモデルを断った
クラウンプラセンタリアの起源は白亜紀後期に遡り,パレオセーン/エオセーンに明確な順序多様化があった.

結論:

新しいベイジアン方法論は完全なゲノムと数千種の分析を可能にします
このアプローチは,以前は難解な種多様化に関する研究課題に取り組んでいます.
この方法は,種レベルでの系統学的データを要求する動物と植物の多様化の他の論争の的ケースに適用できます.

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