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Updated: Oct 9, 2025

Assessment of Global DNA Double-Strand End Resection using BrdU-DNA Labeling coupled with Cell Cycle Discrimination Imaging
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HELQはRPAとRAD51によって調節される二重機能のDSB修復酵素です

Roopesh Anand1, Erika Buechelmaier2,3, Ondrej Belan1

  • 1DSB Repair Metabolism Laboratory, The Francis Crick Institute, London, UK.

Nature
|December 23, 2021
PubMed
まとめ

HELQタンパク質はDNA修復においてヘリコースとして作用し,DNA鎖を冷却する二重の役割を果たします. その機能はRAD51とRPAによって調節され,二重鎖の断裂修復経路に影響を与えます.

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