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Updated: Aug 11, 2026

Using X-ray Crystallography, Biophysics, and Functional Assays to Determine the Mechanisms Governing T-cell Receptor Recognition of Cancer Antigens
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抗原がIaと相互作用し,T細胞によって認識されるために必要な抗原の構造特性

A Sette, S Buus, S Colon

    Nature
    |July 5, 1987
    PubMed
    まとめ

    この研究は,T細胞の認識とIa分子との相互作用に不可欠なキーペプチド残基を明らかにしています. あるモデルは,これらの残留物がペプチド抗原IaとT細胞受容体との間の相互作用を橋渡しすることを示唆しています.

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