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X染色体不活性化から逃れる遺伝子は,バルブミオフィブロブラストの性差を調節する

Brian A Aguado1,2,3,4, Cierra J Walker5,6, Joseph C Grim1,2

  • 1Department of Chemical and Biological Engineering (B.A.A., J.C.G., B.J.V., A.G.R., K.S.A.), University of Colorado, Boulder.

Circulation
|January 10, 2022
PubMed
まとめ

大動脈弁の狭窄の性差には 異なる分子経路が関係しています X染色体不活性化に逃れた遺伝子は,女性におけるミオフィブロブラストの活性化に寄与し,疾患の進行に影響を与えます.

キーワード:
大動脈弁の狭窄バイオコンパティブルな材料ハイドロゲル性別に関する特徴

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