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Updated: Oct 6, 2025

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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スカブロリドAとノミナル・スカブロリドBの総合成

Zhanchao Meng1, Alois Fürstner1

  • 1Max-Planck-Institut für Kohlenforschung, 45470 Mülheim/Ruhr, Germany.

Journal of the American Chemical Society
|January 19, 2022
PubMed
まとめ

研究者は,スケブロリドBをイソメライズすることによって,海洋天然産物スケブロリドAを合成しました. この研究は,新型のカーボサイクルのコア構造を含む,ポリサイクルのノルメブラノイドを合成する重要なステップを明らかにしています.

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