半サンドイッチロジウム/イリジウムのビルディングブロックを用いた複合キラルラジアルのステレオセレクティブ自己組み立て [5]
Zheng Cui1, Xiang Gao1, Yue-Jian Lin1
1State Key Laboratory of Molecular Engineering of Polymers, Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, Department of Chemistry, Fudan University, Shanghai 200433, P. R. China.
Journal of the American Chemical Society
|January 26, 2022
まとめ
この研究は,自己組立を用いたキラル・ラディアル [5] 鎖のステレオ選択的合成を実証している. キラルリガンドは,制御された平面と螺旋のキラル性を持つ複雑な構造の形成を導いた.
科学分野:
- 超分子化学
- 有機金属化学
- ステレオ化学
背景:
- 機械的に相互接続された分子 (MIM) は,ユニークな性質を持つ複雑な構造です.
- MIMのステレオ化学を制御することは,その機能にとって極めて重要です.
- チラルの構成要素は 非対称合成に不可欠です
研究 の 目的:
- キラル・ラディアル [5] チェーンナンのステレオ選択的合成を達成する.
- MIM構築におけるキラルリガンドの役割を調査する.
- セルフアセンブリによる ステレオ化学的結果を探るため
主な方法:
- ビデント酸リガンドとl-アラニン残留物の自己組み立て
- 二核半サンドイッチ有機金属ロジウム (III) /イリジウム (III) クリップによる複合.
- 構造の解明のための単一結晶X線 difraktion.
主要な成果:
- 2つのキラル・ラディアル [5]ケテナンの1段階のステレオ選択合成が成功しました.
- 単一の平面と螺旋のキラリティを持つ複雑なステレオ化学構造の解明.
- d-アラニン残留物を用いて対極キラリティの実証
結論:
- リガンドにおける点キラリティの導入は,MIMの効率的なステレオ選択的構築を可能にします.
- 自己組み立ては 複雑なキラルな 機械的に繋がった分子への強力な経路を提供します
- チラルの有機金属クリップは,ステレオ化学的結果の指示に有効です.
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