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Updated: Oct 5, 2025

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統合失調症

Sameer Jauhar1, Mandy Johnstone2, Peter J McKenna3

  • 1Department of Psychological Medicine, Institute of Psychiatry, Psychology, and Neuroscience, King's College, London, UK.

Lancet (London, England)
|January 30, 2022
PubMed
まとめ

統合失調症は 複雑な脳疾患で 男性と女性に 異なる影響があり 結果も様々です 研究は,現在と将来の治療戦略とともに,遺伝的,環境的,神経生物学的な基盤を探索します.

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Schizophrenia, a complex psychiatric disorder, has been historically misunderstood. Early psychological theories attributed its origins to childhood trauma and unresponsive parenting. However, contemporary research largely rejects these notions, favoring the vulnerability-stress hypothesis. This model proposes that individuals with a genetic predisposition to schizophrenia may develop the disorder following exposure to significant environmental stressors. Notably, studies on high-risk...
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Schizophrenia is a neurodevelopmental disorder whose origins are rooted in complex genetic components. Despite our burgeoning understanding, the pathophysiology of this disorder remains incompletely deciphered.
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Schizophrenia, a severe psychiatric disorder, arises from a complex interplay of biological factors, including genetic predisposition, structural brain abnormalities, neurotransmitter dysregulation, and developmental irregularities. These factors collectively contribute to the onset and progression of the disorder, which typically manifests in late adolescence or early adulthood.
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