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Updated: Oct 4, 2025

Mapping the Binding Site of an Aptamer on ATP Using MicroScale Thermophoresis
08:09

Mapping the Binding Site of an Aptamer on ATP Using MicroScale Thermophoresis

Published on: January 7, 2017

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温度調節 安定性,リガンド結合 (Mg2+とATP),およびGroEL-GroES複合体のステイキオメトリ

Thomas E Walker1, Mehdi Shirzadeh1, He Mirabel Sun1

  • 1Department of Chemistry, Texas A&M University, College Station, Texas 77843, United States.

Journal of the American Chemical Society
|February 2, 2022
PubMed
まとめ

GroELのようなチャペロニンは 細胞機能に不可欠です この研究は,温度がGroELとGroEL-GroES複合体を著しく不安定化し,タンパク質の折りたたみに不可欠なATP結合とステキオメトリーに影響を与えることを明らかにしています.

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