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Updated: Oct 4, 2025

Millisecond Hydrogen/Deuterium-Exchange Mass Spectrometry for the Study of Alpha-Synuclein Structural Dynamics Under Physiological Conditions
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異常な (ヒドロキシ) プロリンデウテリウム含有量は,水素化学質を再定義する

Hassan Gharibi1, Alexey L Chernobrovkin1,2, Gunilla Eriksson3

  • 1Division of Physiological Chemistry I, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, SE-171 77 Stockholm, Sweden.

Journal of the American Chemical Society
|February 2, 2022
PubMed
まとめ

脊椎動物の骨のコラーゲンはプロリンとヒドロキシプロリンに意外に高いデュテリウム濃度を示し",あなたはあなたが食べるもの"という理論に異議を唱えます この発見は 食事による説明を超えて 生物学的デウテリウム濃縮に関する 新しい洞察を明らかにしています

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¹H NMR of Labile Protons: Deuterium (²H) Substitution

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