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Updated: Oct 4, 2025

Author Spotlight: Flow Cytometric Determination of Pyroptosis in Avian Cells
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ストレプトコクスの発酵性エクソトキシンBはGSDMAを分裂させ,発酵性炎症を引き起こす

Wanyan Deng1,2,3, Yang Bai1,4, Fan Deng1,4

  • 1The Center for Microbes, Development and Health, Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai, China.

Nature
|February 3, 2022
PubMed
まとめ

Streptococcus pyogenes の細菌の SpeB プロテアゼはガスダーミンA (GSDMA) を割って,熱死を引き起こす. このGSDMAの活性化は この危険な皮膚病原体に対する 宿主の防御に不可欠です

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