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Updated: Oct 4, 2025

Free Radicals in Chemical Biology: from Chemical Behavior to Biomarker Development
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B12依存型ラジカルSAMメチルトランスファーゼの結晶学的スナップショット

Cameron D Fyfe1, Noelia Bernardo-García1, Laura Fradale1

  • 1Université Paris-Saclay, INRAE, AgroParisTech, Micalis Institute, ChemSyBio, Jouy-en-Josas, France.

Nature
|February 3, 2022
PubMed
まとめ

この研究では,メタンの生成に不可欠な,独特のB12依存型 SAM酵素であるMmp10の原子構造が明らかになりました. 発見は,この酵素複合体がC-メチル化反応をどのように触媒化するかを明らかにしています.

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