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Updated: May 11, 2026

Detecting Somatic Genetic Alterations in Tumor Specimens by Exon Capture and Massively Parallel Sequencing
11:02

Detecting Somatic Genetic Alterations in Tumor Specimens by Exon Capture and Massively Parallel Sequencing

Published on: October 18, 2013

19.5K

25,000人の患者の潜在的な臨床シーケンシングからの転移パターンのゲノム特性

Bastien Nguyen1, Christopher Fong1, Anisha Luthra1

  • 1Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Cell
|February 5, 2022
PubMed
まとめ

ゲノム変異は癌の転移を促し 癌による死亡の主な原因となります この研究では25,000人の転移性がん患者を分析し ゲノム変化,染色体不安定性,転移性腫瘍の50種類間の関連性を明らかにしました

キーワード:
DNAシーケンシング癌について臨床シーケンシングゲノム学メタスタシス分子プロファイリング変異次世代シーケンシングオーガノトロピズム臓がん

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