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Updated: Oct 4, 2025

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ピリミジン阻害剤は,ヌクレオシド類似剤と連携してSARS-CoV-2を阻害する

David C Schultz1, Robert M Johnson2, Kasirajan Ayyanathan3

  • 1Department of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia, PA, USA. dschultz@pennmedicine.upenn.edu.

Nature
|February 7, 2022
PubMed
まとめ

研究者らは,SARS-CoV-2に対する1万8000の薬剤をスクリーニングし,122の薬剤が抗ウイルス性であることを確認した. ヌクレオシド類似剤とピリミジン阻害剤を組み合わせると,COVID-19に対する相乗効果があり,有望な治療戦略を示しています.

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