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Updated: Oct 4, 2025

A Two-Step Protocol for Umpolung Functionalization of Ketones Via Enolonium Species
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エンタルピー制御された核愛性機能化によるピリミジンのC2選択的,機能群異なったアミネーション

Won Seok Ham1,2, Hoonchul Choi1,2, Jianbo Zhang1,2

  • 1Center for Catalytic Hydrocarbon Functionalizations, Institute for Basic Science (IBS), Daejeon 34141, South Korea.

Journal of the American Chemical Society
|February 9, 2022
PubMed
まとめ

研究者は,ヘテロアリルアミン,特に2-アミノピリミジンを直接C-H機能化によって合成するための新しい方法を開発した. この突破により 選択的なC2-N結合が形成され 新しい生物活性分子の発見に 極めて重要です

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