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Updated: Oct 4, 2025

Porous Silicon Microparticles for Delivery of siRNA Therapeutics
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ヘアピン型のsiRNAベースの球状核酸

Matthew K Vasher1,2, Gokay Yamankurt2,3, Chad A Mirkin1,2,4

  • 1Department of Biomedical Engineering, Northwestern University, 2145 Sheridan Road, Evanston, Illinois 60208, United States.

Journal of the American Chemical Society
|February 10, 2022
PubMed
まとめ

新しいヘアピンのような小さな干渉RNA-球状核酸 (siRNA-SNA) 構造は,配送の課題を克服する. この新しい設計は,siRNAの安定性を高め,毒性を軽減し,治療用途の遺伝子ノックダウン効率を改善します.

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