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Updated: Oct 3, 2025

An Integrated System to Remotely Trigger Intracellular Signal Transduction by Upconversion Nanoparticle-mediated Kinase Photoactivation
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An Integrated System to Remotely Trigger Intracellular Signal Transduction by Upconversion Nanoparticle-mediated Kinase Photoactivation

Published on: August 30, 2017

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光誘発型アポプトシス細胞死 (PTA) 光誘発型外向型陽子ポンプを用いたロドプシン・アーカイロドプシン-3

Shin Nakao1, Keiichi Kojima1,2, Yuki Sudo1,2

  • 1Division of Pharmaceutical Sciences, Okayama University, Okayama 700-8530, Japan.

Journal of the American Chemical Society
|February 17, 2022
PubMed
まとめ

研究者は,光活性化プロトンポンプを使用して細胞内pHを操作することによって,プログラムされた細胞死 (アポトーシス) を制御するための新しい光遺傳学的方法を開発しました. この技術である光誘発性アポトーシス (PTA) は,様々な生物で精密な細胞除去の可能性を示しています.

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