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Updated: Oct 2, 2025

Global Identification of Co-Translational Interaction Networks by Selective Ribosome Profiling
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ERタンパク質ターゲティング中のリボソームのNACからSRPへの信号配列移転のメカニズム

Ahmad Jomaa1, Martin Gamerdinger2, Hao-Hsuan Hsieh3

  • 1Department of Biology, Institute of Molecular Biology and Biophysics, ETH Zurich, 8093 Zurich, Switzerland.

Science (New York, N.Y.)
|February 24, 2022
PubMed
まとめ

ポリペプチド関連複合体 (NAC) は,新生ポリペプチドと相互作用することによって,タンパク質標的を調節する. NACは,シグナル認識粒子 (SRP) アクセスを管理するために2つのドメインを使用し,誤ったターゲティングを防ぐために正しいタンパク質の局所化を保証します.

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