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Updated: Oct 2, 2025

Author Spotlight: Advanced Single-Molecule Techniques for Investigating Telomeric Protein-DNA Interactions
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Author Spotlight: Advanced Single-Molecule Techniques for Investigating Telomeric Protein-DNA Interactions

Published on: August 30, 2024

893

TPP1-POT1によるヒトテロメラーゼ募集の構造的基礎

Zala Sekne1, George E Ghanim1, Anne-Marie M van Roon1

  • 1MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, UK.

Science (New York, N.Y.)
|February 24, 2022
PubMed
まとめ

ゲノム安定性にとって重要なテロメラーゼは,TPP1-POT1経由でテロメアに誘導されます. 構造的な洞察は この複合体が DNA を安定させ テロメラーゼの活動を制御する方法を明らかにします

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