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Updated: Oct 2, 2025

Protocol for the Solid-phase Synthesis of Oligomers of RNA Containing a 2'-O-thiophenylmethyl Modification and Characterization via Circular Dichroism
11:37

Protocol for the Solid-phase Synthesis of Oligomers of RNA Containing a 2'-O-thiophenylmethyl Modification and Characterization via Circular Dichroism

Published on: July 28, 2017

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橋渡しフォスフォラミド酸エステル中間体によるアミノアシルRNAの潜在的プレバイオティック合成

Samuel J Roberts1, Ziwei Liu1, John D Sutherland1

  • 1MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, U.K.

Journal of the American Chemical Society
|March 1, 2022
PubMed
まとめ

研究者達は 生命の初期に不可欠な アミノアシルRNAを合成する 新しいプリバイオティクスの経路を発見しました この方法は高エネルギーの中間物質を避け,エウテクティック条件下で働き,RNAの世界化学の洞察を提供します.

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