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Updated: Oct 1, 2025

Investigating Protein Sequence-structure-dynamics Relationships with Bio3D-web
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ダイナミックなタンパク質集合体における高エネルギー状態の構造決定

John B Stiller1, Renee Otten1, Daniel Häussinger2

  • 1Department of Biochemistry and Howard Hughes Medical Institute, Brandeis University, Waltham, MA, USA.

Nature
|March 3, 2022
PubMed
まとめ

研究者は,低エネルギータンパク質状態の構造を決定するために,NMRスペクトロスコピーによる偽接触シフト (PCS) とカール・パーセル・メイブーム・ギル (CPMG) のリラクゼーション分散 (PCS-CPMG) を組み合わせた新しい方法を開発した. この技術は,機能中のタンパク質の動力学,運動学,熱力学を明らかにします.

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