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Updated: Oct 1, 2025

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In vivo ホモロジー・ディレクテッド・リペア・イン・カーディオミオサイト

Yanjiang Zheng1, Nathan J VanDusen2, Catalina E Butler2

  • 1Department of Biochemistry, West China School of Basic Medical Sciences & Forensic Medicine, Sichuan University, Chengdu, China (Y.Z.).

Circulation
|March 7, 2022
PubMed
まとめ

No abstract available in PubMed .

キーワード:
CRISPRに関連したタンパク質9ゲノム編集ホモロジー指向の dsDNA 破損修復筋細胞,心臓

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Homologous Recombination02:31

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The basic reaction of homologous recombination (HR) involves two chromatids that contain DNA sequences sharing a significant stretch of identity. One of these sequences uses a strand from another as a template to synthesize DNA in an enzyme-catalyzed reaction. The final product is a novel amalgamation of the two substrates. To ensure an accurate recombination of sequences, HR is restricted to the S and G2 phases of the cell cycle. At these stages, the DNA has been replicated already and the...
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