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Updated: Oct 1, 2025

PCR Mutagenesis, Cloning, Expression, Fast Protein Purification Protocols and Crystallization of the Wild Type and Mutant Forms of Tryptophan Synthase
09:31

PCR Mutagenesis, Cloning, Expression, Fast Protein Purification Protocols and Crystallization of the Wild Type and Mutant Forms of Tryptophan Synthase

Published on: September 26, 2020

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トリプトファンが枯渇すると,トリプトファンをフェニララニンに代用する物質が生じる

Abhijeet Pataskar1, Julien Champagne1, Remco Nagel1

  • 1Division of Oncogenomics, Oncode institute, The Netherlands Cancer Institute, Amsterdam, The Netherlands.

Nature
|March 10, 2022
PubMed
まとめ

癌細胞はトリプトファンが少ないにもかかわらず,トリプトファンのコドンをフェニララニンに再配分することでタンパク質を合成します. この代替的な解読は 腫瘍の免疫と機能に影響を与える "代用物質"を生み出します

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