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Updated: Sep 30, 2025

Cercosporin-Photocatalyzed [4+1]- and [4+2]-Annulations of Azoalkenes Under Mild Conditions
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自然製品生物合成におけるヒドロキナフトキノンの暗号的酸化トランスアミネーション

Tomohiro Noguchi1, Shota Isogai1, Tohru Terada1,2

  • 1Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, JAPAN.

Journal of the American Chemical Society
|March 16, 2022
PubMed
まとめ

研究者らは,ピリドクサル5'-リン酸 (PLP) に依存する新しい酵素であるNphEを発見した. この酵素は,トランスアミネーションと酸化の両方で酸素 (O2) を独特に使用し,天然製品生物合成の重要な中間物質である8-アミノフラビオリン (8-AF) を形成します.

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