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Updated: Sep 30, 2025

From Constructs to Crystals – Towards Structure Determination of β-barrel Outer Membrane Proteins
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Published on: July 4, 2016

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クリオ・エム構造は,細菌の外膜タンパク質の折り畳みの複数の段階を明らかにする

Matthew Thomas Doyle1, John R Jimah2, Tyrone Dowdy3

  • 1Genetics and Biochemistry Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

Cell
|March 16, 2022
PubMed
まとめ

バクテリアの外膜タンパク質組立装置 (BAM) は,外膜の弾性を使用して,トランスメブランβバレルタンパク質を折りたたむ. このプロセスは特定のタンパク質の相互作用と 中間構造を含み タンパク質の折りたたみの新しいメカニズムを明らかにします

キーワード:
BAM について膜ダイナミクス膜タンパク質の折り畳み外膜タンパク質β バレル

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