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Updated: Sep 30, 2025

A "Dual-Addition" Calcium Fluorescence Assay for the High-Throughput Screening of Recombinant G Protein-Coupled Receptors
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治療用のSTING活性化剤を合成するキナーゼ-cGASカスケード

John A McIntosh1, Zhijian Liu2, Brian M Andresen3

  • 1Process Research & Development, Merck & Co., Inc., Rahway, NJ, USA. john.mcintosh1@merck.com.

Nature
|March 17, 2022
PubMed
まとめ

複雑な分子の効率的な合成を可能にします この研究では,新しい治療薬のバイオカタリシスを実証する,STING活性化剤であるMK-1454の生成のための酵素カスケードが詳細に示されています.

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