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Updated: Sep 30, 2025

Induction of Intestinal Inflammation by Adoptive Transfer of CBir1 TCR Transgenic CD4+ T Cells to Immunodeficient Mice
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ヒトの腸内細菌は,TΗを調節する胆酸代謝産物を生成する

Donggi Paik1, Lina Yao2, Yancong Zhang3,4

  • 1Department of Immunology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.

Nature
|March 17, 2022
PubMed
まとめ

腸内細菌はTヘルパー17 (TH17) 細胞の分化を阻害する胆酸を生成する. これらの免疫調節性胆酸の濃度低下は炎症性腸疾患と関連しており,腸炎症の役割を示唆しています.

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