関連する実験動画

Updated: Sep 30, 2025

Screening for Functional Non-coding Genetic Variants Using Electrophoretic Mobility Shift Assay EMSA and DNA-affinity Precipitation Assay DAPA
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Screening for Functional Non-coding Genetic Variants Using Electrophoretic Mobility Shift Assay EMSA and DNA-affinity Precipitation Assay DAPA

Published on: August 21, 2016

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人間における遺伝的関連には複数の因果関係がある

Nathan S Abell1, Marianne K DeGorter2, Michael J Gloudemans3

  • 1Department of Genetics, School of Medicine, Stanford University, Stanford, CA 94305, USA.

Science (New York, N.Y.)
|March 17, 2022
PubMed
まとめ

多くの遺伝的関連は,連結不均衡 (LD) の複数の因果的な変異を含んでいる. 私たちの研究では,大量並列レポーターアッセイ (MPRA) を用いて,17%以上の表現定量特征ロシ (eQTL) が独立したアレル効果を有し,複雑な遺伝構造を明らかにしました.

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