関連する実験動画

Updated: Sep 29, 2025

Analyzing Tumor and Tissue Distribution of Target Antigen Specific Therapeutic Antibody
07:36

Analyzing Tumor and Tissue Distribution of Target Antigen Specific Therapeutic Antibody

Published on: May 16, 2020

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腫瘍反応性抗体は,非結合性および自己反応性前体から進化する

Roei D Mazor1, Nachum Nathan2, Amit Gilboa3

  • 1Department of Immunology, Weizmann Institute of Science, Rehovot 7610001, Israel; Department of Biological Regulation, Weizmann Institute of Science, Rehovot 7610001, Israel.

Cell
|March 19, 2022
PubMed
まとめ

卵巣がんにおける抗体分泌細胞 (ASC) は,腫瘍を標的とする抗体を産生する. ソマティック・ハイパーミューテーション (SHM) は,表面オートアンチゲンに対する抗体抗腫瘍反応を誘発し,がんの診断と治療の可能性を秘めています.

キーワード:
B セルHGSOC についてMMP14 についてMT1-MMP について抗体抗体媒介免疫反応オートアンチボディ癌について卵巣がんプラズマ細胞

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