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Updated: Sep 29, 2025

The Synthesis, Characterization and Reactivity of a Series of Ruthenium N-triphosPh Complexes
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The Synthesis, Characterization and Reactivity of a Series of Ruthenium N-triphosPh Complexes

Published on: April 10, 2015

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ルテニウムポリピリジル複合体 単分子チェア型G四重複合体

Kane T McQuaid1, Shuntaro Takahashi2, Lena Baumgaertner1

  • 1Department of Chemistry, University of Reading, Whiteknights, Reading RG6 6AD, U.K.

Journal of the American Chemical Society
|March 24, 2022
PubMed
まとめ

ルテニウム複合体 Λ-[Ru(phen) 2(qdppz) ]2+は,G-四重複のDNA構造をエナチオ特異的に結合する. この複合体はDNA複製を強く阻害し,G-四重複のトポロジを標的とする治療の可能性を提供します.

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