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Updated: Sep 28, 2025

Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2
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TMPRSS2阻害剤は,パン-SARS-CoV-2の予防と治療として作用する

Tirosh Shapira1, I Abrrey Monreal2, Sébastien P Dion3

  • 1Department of Microbiology and Immunology, Life Sciences Institute, University of British Columbia, Vancouver, British Columbia, Canada.

Nature
|March 28, 2022
PubMed
まとめ

新しい化合物であるN-0385は,II型トランスメブランセリンタンパク質酶 (TTSP) を標的として,SARS-CoV-2感染を効果的に抑制する. この小さな分子は,COVID-19とその新たな変種に対する早期治療の選択肢として有望であることが示されています.

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