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Updated: Sep 28, 2025

Isolation, Characterization, and Purification of Macrophages from Tissues Affected by Obesity-related Inflammation
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Isolation, Characterization, and Purification of Macrophages from Tissues Affected by Obesity-related Inflammation

Published on: April 3, 2017

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肥満は炎症性疾患の病理と治療への反応を変化させる

Sagar P Bapat1,2,3,4,5,6, Caroline Whitty7,8, Cody T Mowery8,9,10

  • 1NOMIS Center for Immunobiology and Microbial Pathogenesis, The Salk Institute for Biological Studies, La Jolla, CA, USA. sagar.bapat@ucsf.edu.

Nature
|March 31, 2022
PubMed
まとめ

肥満はアトピー性皮膚炎における免疫反応を変化させ,炎症をTヘルパー2 (TH2) からTヘルパー17 (TH17) 細胞にシフトさせます. T細胞におけるPPARγの活性化は,肥満に起因する免疫不調を防ぐための鍵です.

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