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Updated: Sep 28, 2025

Generation of Two-color Antigen Microarrays for the Simultaneous Detection of IgG and IgM Autoantibodies
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Generation of Two-color Antigen Microarrays for the Simultaneous Detection of IgG and IgM Autoantibodies

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癌で局所的に生成された自己抗体

Sara M Centuori1, Deepta Bhattacharya2

  • 1Department of Medicine, University of Arizona College of Medicine, Tucson, AZ, USA; Department of Immunobiology, University of Arizona College of Medicine, Tucson, AZ, USA; University of Arizona Cancer Center, Tucson, AZ, USA.

Cell
|April 1, 2022
PubMed
まとめ

卵巣がんの腫瘍に浸透したB細胞はB細胞を活性化し,自己抗体を産生する. マトリックス金属タンパク質酶14 (MMP14) は,自己抗原であり,三次リンパ性構造内でこのプロセスを駆動する.

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