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Updated: Sep 28, 2025

Purification and Aggregation of the Amyloid Precursor Protein Intracellular Domain
10:08

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CCT2は固体タンパク質のクリアランスのためのアグレファジー受容体である

Xinyu Ma1, Caijing Lu1, Yuting Chen2

  • 1State Key Laboratory of Membrane Biology, Beijing, China; Tsinghua-Peking Center for Life Sciences, Beijing 100084, China; School of Life Sciences, Tsinghua University, Beijing 100084, China.

Cell
|April 2, 2022
PubMed
まとめ

研究者らは,CCT2を新種のオートファジー受容体として発見した. このタンパク質は固体タンパク質を 選択的に除去し 神経退行性疾患のメカニズムに 新たな洞察をもたらします

キーワード:
CCT2 についてFUS についてガバラップハンティントン病LC3 についてNBR1 についてP62 についてSOD1 についてTAX1BP1についてトリックスアグレファジーオートファジー付き添いチャペロニンハンティングチン神経変性段階分離プロテイン・アグレガットタンパク質の集積タウ

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