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Updated: Sep 28, 2025

Engineering Antiviral Agents via Surface Plasmon Resonance
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SARS-CoV-2エンベロープタンパク質のpHおよびカルシウム依存性アロマティックネットワーク

João Medeiros-Silva1, Noah H Somberg1, Harrison K Wang1

  • 1Department of Chemistry, Massachusetts Institute of Technology, 170 Albany Street, Cambridge, Massachusetts 02139, United States.

Journal of the American Chemical Society
|April 5, 2022
PubMed
まとめ

SARS-CoV-2 Eタンパク質チャネルは,アロマティックネットワークを通じて開きます. 酸性pHとカルシウムイオンは形状の変化を促進し,毛穴の広さと水のアクセシビリティを増加させ,新しい阻害剤の標的を示唆する.

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