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Updated: Sep 27, 2025

Isolation Protocol of Mouse Monocyte-derived Dendritic Cells and Their Subsequent In Vitro Activation with Tumor Immune Complexes
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Isolation Protocol of Mouse Monocyte-derived Dendritic Cells and Their Subsequent In Vitro Activation with Tumor Immune Complexes

Published on: May 31, 2018

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単細胞のFcγR媒介のSARS-CoV-2感染は炎症を活性化する

Caroline Junqueira1,2,3, Ângela Crespo4,5, Shahin Ranjbar4,6

  • 1Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA. caroline.junqueira@childrens.harvard.edu.

Nature
|April 6, 2022
PubMed
まとめ

SARS-CoV-2は単細胞に感染し,炎症体の活性化と熱死を引き起こす. この炎症性細胞死はウイルスの複製を中止するが,COVID-19の全身性炎症に寄与する.

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Isolation, Transfection, and Culture of Primary Human Monocytes

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Inflammatory Response

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Inflammatory Response I: Vascular and Cellular

The inflammatory response is the body's defense against infection, injury, or irritation from bacteria, trauma, toxins, or heat. Inflammation helps locate and destroy pathogens and remove damaged tissue elements to heal the body. During this initial phase, fluid, blood products, and nutrients migrate to the injured area, resulting in redness, heat, swelling, ache, and loss of function. Moreover, signs of systemic inflammation include fever, increased WBC count, malaise, anorexia, nausea,...
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