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膜域内のポケットをターゲットにSTINGの活性化

Defen Lu1, Guijun Shang1, Jie Li2

  • 1Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, TX, USA.

Nature
|April 7, 2022
PubMed
まとめ

新種の小分子C53は STINGタンパク質の活性化を高め 生まれながらの免疫を高めます この発見は,STINGオリゴマーの安定化により,ワクチンやがん免疫療法の開発の新たな道を開きます.

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