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Updated: Sep 27, 2025

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菌糸体抗CBASSと抗Pycsar核酸は細菌の免疫を低下させる

Samuel J Hobbs1,2, Tanita Wein3, Allen Lu1,2

  • 1Department of Microbiology, Harvard Medical School, Boston, MA, USA.

Nature
|April 8, 2022
PubMed
まとめ

バクテリアの抗菌体防御システム,循環性オリゴヌクレオチドベースの抗菌体シグナル伝達 (CBASS) と抗菌体抵抗のためのピリミジンサイクラゼシステム (Pycsar) は,新しいファグタンパク質によって対抗されます. これらの抗CBASS (Acb) と抗Pycsar (Apyc) タンパク質は周期的な核酸信号を分解し,細菌の免疫を阻害する.

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