関連する実験動画

Updated: Sep 27, 2025

A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis

A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis

Published on: December 28, 2012

COVID-19に関連した急性心筋炎の流行,特徴,結果

Enrico Ammirati¹, Laura Lupi², Matteo Palazzini¹

¹De Gasperis Cardio Center and Transplant Center, Niguarda Hospital, Milano, Italy (E.A., M.P., P.P. F.S., M.C., C.G.).

|April 11, 2022

まとめ

急性心筋炎 (AM) は,COVID-19のまれな心血管合併症であり,1000人当たり2.4-4.1人に発生する. 結末は肺炎の存在によって異なるが,COVID-19に関連した肺炎患者の死亡率は高い.

科学分野:

心臓病科
感染症
公衆衛生

背景:

急性心筋炎 (AM) は,COVID-19の潜在的心血管合併症である.
COVID-19に関連したAMの流行とアウトカムに関するデータは限られている.

研究の目的:

COVID-19に関連したAMの流行,特徴,管理,アウトカムを決定する.
住院中のCOVID-19患者のAM結果に影響を与える要因を分析する.

主な方法:

米国とヨーロッパの23の病院で,入院した56,963人のコホート研究.
含有基準:COVID-19とAM診断の入院 (心内膜組織生検またはCMRの検出でトロポニンの値上昇).
患者の人口統計,臨床表現,治療,入院/120日経過の分析

主要な成果:

確固たる/ 可能性のあるAMの罹患率は2. 4/1000であり,可能なAMは4. 1/1000の入院でした.
平均年齢38歳.女性38.9%. 胸の痛みと呼吸不全は一般的な症状でした.
症例の57.4%はCOVID-19肺炎ではなく,38.9%は fulminant 症状でした.
病院での複合アウトカム (死亡率/メカニカルサポート) は20. 4%でした. 120日間の死亡率は6. 6%で,肺炎では有意に高かった (15. 1% vs 0%).
左心室の放出分子は 40%から55%に大幅に改善されました.

結論:

COVID-19に関連したAMは希少で,1000人当たり2.4-4.1人に影響する.
AMはしばしば肺炎なしで現れ,血動力学的不安定性につながる可能性があります.
結末は併発性肺炎の有無によって影響され,肺炎の有無では予後が悪い.

キーワード:

コロナウイルス MRI について SARS-CoV-2について心臓病について心筋炎結果

さらに関連する動画

Noninvasive Assessment of Cardiac Abnormalities in Experimental Autoimmune Myocarditis by Magnetic Resonance Microscopy Imaging in the Mouse

Noninvasive Assessment of Cardiac Abnormalities in Experimental Autoimmune Myocarditis by Magnetic Resonance Microscopy Imaging in the Mouse

Published on: June 20, 2014

Primary Outcome Assessment in a Pig Model of Acute Myocardial Infarction

Primary Outcome Assessment in a Pig Model of Acute Myocardial Infarction

Published on: October 14, 2016

関連する概念動画

Myocarditis II: Clinical Features and Diagnostic Tests

Myocarditis II: Clinical Features and Diagnostic Tests

Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...

Myocarditis III: Medical Management

Myocarditis III: Medical Management

Myocarditis: Comprehensive Medical ManagementMyocarditis, the heart muscle inflammation, requires a comprehensive medical management strategy that addresses the underlying cause, provides supportive care, manages symptoms, and reduces cardiac workload.Infections and Autoimmune CausesAdminister appropriate antimicrobial therapy when an infectious agent causes myocarditis. For instance, penicillin treats infections caused by Group A Streptococcus. In cases where autoimmune processes are...

Myocarditis I: Introduction

Myocarditis I: Introduction

Myocarditis is inflammation of the myocardium, which is the muscular layer of the heart.EtiologyMyocarditis has a diverse etiology, including a wide range of infectious and non-infectious causes:Infectious CausesViral: Common viruses include Coxsackie A and B, adenovirus, parvovirus B19, enteroviruses, and influenza A.Bacterial: Examples include infections caused by Streptococcus, Staphylococcus, and Mycoplasma species.Rickettsial: Infections like Rocky Mountain spotted fever can result in...

Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations

Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations

The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...

Acute Coronary Syndrome I: Introduction

Acute Coronary Syndrome I: Introduction

Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...

Acute Coronary Syndrome III: Diagnostic Studies

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...