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Updated: Sep 27, 2025

Static Adhesion Assay for the Study of Integrin Activation in T Lymphocytes
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Published on: June 13, 2014

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粘着性GPCRの結合ペプチド活性化メカニズム ADGRG2とADGRG4

Peng Xiao1,2,3, Shengchao Guo3, Xin Wen3

  • 1Department of Clinical Laboratory, The Second Hospital, and Advanced Medical Research Institute, Cheeloo College of Medicine, Shandong University, Jinan, China.

Nature
|April 14, 2022
PubMed
まとめ

粘着Gタンパク質結合受容体 (aGPCRs) は,凍結EM構造によって明らかにされた,結合されたスタッケル配列を通じて活性化されます. このメカニズムは,これらの古代受容体の新しいペプチドアゴニストとアンタゴニストの設計に情報を与えます.

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