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Updated: Sep 27, 2025

Static Adhesion Assay for the Study of Integrin Activation in T Lymphocytes
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Static Adhesion Assay for the Study of Integrin Activation in T Lymphocytes

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粘着GPCRの結合ペプチド活性化のための構造的基礎

Yu-Qi Ping1,2,3,4, Peng Xiao1,5, Fan Yang1,3,5,6

  • 1Key Laboratory Experimental Teratology of the Ministry of Education, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, China.

Nature
|April 14, 2022
PubMed
まとめ

粘着Gタンパク質結合受容体 (aGPCRs) は,結合されたStachel配列によって活性化されます. Cryo-EM構造は,これらの配列がトランスメブラン領域に結合し,受容体活性化とGs結合を媒介することを明らかにします.

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