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Updated: Sep 27, 2025

Static Adhesion Assay for the Study of Integrin Activation in T Lymphocytes
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粘着GPCRの結合ペプチド活性化メカニズム

Ximena Barros-Álvarez1, Robert M Nwokonko1, Alexander Vizurraga2

  • 1Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA, USA.

Nature
|April 14, 2022
PubMed
まとめ

粘着Gタンパク質結合受容体 (aGPCRs) は,結合アゴニストメカニズムによって活性化されます. Cryo-EM構造は,GPR56とLPHN3受容体がGタンパク質に結合し,GPCRの活性化を明らかにします.

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