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Updated: Jul 18, 2026

Transplantation of Pancreatic Islets Into the Kidney Capsule of Diabetic Mice
10:43

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Published on: October 31, 2007

臓のβ細胞で発現するトランスジェニック自己抗原に対する不耐性および自己抗体

T E Adams, S Alpert, D Hanahan

    Nature
    |January 15, 1987
    PubMed
    まとめ

    トランスジェニックマウスは,シミアンウイルス40 T抗原に対する様々な反応を示しています. ベータ細胞発達の過程で発現が遅延すると,自己免疫反応と不耐性系における臓小島障害が生じます.

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