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Updated: Sep 26, 2025

A Nonviral Approach to Generate Transient Chimeric Antigen Receptor T Cells Using mRNA for Cancer Immunotherapy
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パーソナライズされたがん免疫療法のためのDNAエンジニアリングリンパ球ベースの同類標的化人工抗原提示細胞

Lele Sun1, Fengyun Shen1, Zijian Xiong1

  • 1Institute of Functional Nano & Soft Materials (FUNSOM) Jiangsu Key Lab Carbon Based Functional Materials and Devices, Soochow University, Suzhou 215123, Jiangsu, China.

Journal of the American Chemical Society
|April 19, 2022
PubMed
まとめ

研究者は,非侵襲的な細胞表面工学を使用して,リンパ球ベースの人工抗原提示細胞 (aAPC) を開発しました. これらの設計されたaAPCは vivoでT細胞を効果的に活性化し,先進的な腫瘍免疫療法戦略の有望性を示しています.

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