Jove
Visualize
お問い合わせ
JoVE
x logofacebook logolinkedin logoyoutube logo
JoVEについて
概要リーダーシップブログJoVEヘルプセンター
著者向け
出版プロセス編集委員会範囲と方針査読よくある質問投稿
図書館員向け
推薦の声購読アクセスリソース図書館諮問委員会よくある質問
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experimentsアーカイブ
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教員リソースセンター教員サイト
利用規約
プライバシーポリシー
ポリシー

関連する概念動画

Acute Pyelonephritis I: Introduction01:27

Acute Pyelonephritis I: Introduction

76
Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such...
76
Acute Kidney Injury II: Pathophysiology01:29

Acute Kidney Injury II: Pathophysiology

111
Acute kidney injury (AKI) causes are categorized into three primary categories based on the location of the injury: prerenal, intrarenal (or intrinsic), and postrenal causes. This classification guides clinical management and illustrates how different pathways can impair kidney function.Etiology and Pathophysiology of Acute Kidney Injury1. Prerenal causesEtiology: Prerenal Acute Kidney Injury, the most common type, occurs when reduced blood flow to the kidneys decreases filtration capacity...
111
Acute Kidney Injury I: Introduction01:22

Acute Kidney Injury I: Introduction

100
Introduction:Acute Kidney Injury (AKI) describes a swift decrease in kidney function occurring over hours to days, characterized by the kidneys' failure to remove waste products from the bloodstream. This leads to dangerous complications like metabolic acidosis, fluid overload, and electrolyte imbalances, such as hyperkalemia, which can cause life-threatening arrhythmias. AKI is common in both hospital and outpatient settings, often triggered by dehydration, sepsis, or exposure to nephrotoxic...
100
Acute Pyelonephritis II: Diagnostic Studies and Management01:28

Acute Pyelonephritis II: Diagnostic Studies and Management

60
Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
60
Nephrotic Syndrome I : Introduction01:24

Nephrotic Syndrome I : Introduction

41
Nephrotic Syndrome is a chronic kidney disorder defined by clinical findings such as severe proteinuria, hypoalbuminemia, hyperlipidemia, and edema. These symptoms result from damage to the glomeruli, the kidney’s filtering units, increasing their permeability to proteins.Definition and Meaning:Proteinuria, defined as the loss of more than 3.5 grams of protein per day in adults, is a crucial feature of nephrotic syndrome. This condition is often accompanied by edema, the accumulation of...
41
Acute Kidney Injury IV: Diagnostic Studies and Prevention01:30

Acute Kidney Injury IV: Diagnostic Studies and Prevention

67
Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
67

こちらも読む

関連記事

共著者、ジャーナル、引用グラフによってこの研究に関連する記事。

並び替え
Same author

Long-term eculizumab treatment failure in C3 glomerulonephritis: two case reports.

Clinical kidney journal·2026
Same author

Contactin-1 Membranous Nephropathy Without Neuropathy and Serum Antibodies.

Kidney international reports·2026
Same author

In Reply: Reassessing Cancer Attribution and Methodological Limitations in PLA2R-Associated Membranous Nephropathy.

Mayo Clinic proceedings·2026
Same author

Obinutuzumab or Tacrolimus in Primary Membranous Nephropathy.

The New England journal of medicine·2026
Same author

Low-Dose Rivaroxaban and Cardiovascular Events in Advanced Kidney Disease: The TRACK Randomized Clinical Trial.

JAMA·2026
Same author

Anti-CD38 Therapy With Daratumumab in High-Risk IgA Nephropathy.

Kidney international reports·2026

関連する実験動画

Updated: Sep 26, 2025

Isolation of Glomeruli and In Vivo Labeling of Glomerular Cell Surface Proteins
09:12

Isolation of Glomeruli and In Vivo Labeling of Glomerular Cell Surface Proteins

Published on: January 18, 2019

9.3K

急性グルメロネフリス

Sanjeev Sethi1, An S De Vriese2, Fernando C Fervenza3

  • 1Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.

Lancet (London, England)
|April 24, 2022
PubMed
まとめ
この要約は機械生成です。

グロメルロネフリスは様々な腎臓疾患を 含む. 診断は腎臓生検に依存し,よりよい理解と治療のためのパターンベースのアプローチよりも因果分類に移行しています.

さらに関連する動画

An Efficient Sieving Method to Isolate Intact Glomeruli from Adult Rat Kidney
10:14

An Efficient Sieving Method to Isolate Intact Glomeruli from Adult Rat Kidney

Published on: November 1, 2018

13.9K
A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
09:02

A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion

Published on: February 2, 2021

4.6K

関連する実験動画

Last Updated: Sep 26, 2025

Isolation of Glomeruli and In Vivo Labeling of Glomerular Cell Surface Proteins
09:12

Isolation of Glomeruli and In Vivo Labeling of Glomerular Cell Surface Proteins

Published on: January 18, 2019

9.3K
An Efficient Sieving Method to Isolate Intact Glomeruli from Adult Rat Kidney
10:14

An Efficient Sieving Method to Isolate Intact Glomeruli from Adult Rat Kidney

Published on: November 1, 2018

13.9K
A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
09:02

A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion

Published on: February 2, 2021

4.6K

科学分野:

  • 腎臓科
  • 免疫病理学
  • 腎臓医学

背景:

  • 血流,タンパク質尿,高血圧,腎機能低下が伴う.
  • 急性症状はまれですが,ほとんどの患者は無症状の尿道異常を経験します.
  • 発症はIgA腎不全とC3球球不全の特徴である.

研究 の 目的:

  • グローメルロネフライトの臨床表現,病理,治療について概要を述べる.
  • 病原学的パターンから因果的なメカニズムまで進化する分類を強調する.
  • 免疫複合体,抗中性子細胞抗体関連,C3球膜炎を含む主要な球膜炎サブタイプについて議論する.

主な方法:

  • グローメルーロネフライトの臨床表現と病理学的発見のレビュー
  • 腎臓生検を重視した診断方法の分析
  • 主要なグルメロネフライトの治療戦略の検討

主要な成果:

  • 免疫複合体,抗中性子細胞抗体関連,抗グルメル底膜,C3グルメルパシー,およびモノクローナル免疫グロブリン関連型に分類される.
  • 伝統的なパターンベースの方法よりも,因果的分類アプローチが好まれています.
  • 根本的な原因と病原遺伝的メカニズムを理解することは極めて重要です

結論:

  • グロメルーロネフライトの分類は,因果的な理解に向かって進んでいます.
  • 腎臓の生検は 診断の黄金基準です
  • 多様なグルメロネフライト疾患の理解と管理に役立つ包括的な概要