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Updated: Sep 25, 2025

Sequence-specific Labeling of Nucleic Acids and Proteins with Methyltransferases and Cofactor Analogues
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Sequence-specific Labeling of Nucleic Acids and Proteins with Methyltransferases and Cofactor Analogues

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メチルデヒドロフォスミドミシン成熟のメカニズム: 鎖の延長を可能にするためにオレフィネーションを使用する

Xiaojun Li1, Shan Xue2, Yisong Guo2

  • 1Department of Chemistry, North Carolina State University, Raleigh, North Carolina 27695, United States.

Journal of the American Chemical Society
|April 28, 2022
PubMed
まとめ

鉄/2-オックスグルタレット依存酵素は,複雑な天然製品の合成を触媒化する. この研究は,C−C結合形成と脱メチル化を含む,デヒドロフォスミドミシン生物合成のための新しい2段階のメカニズムを明らかにしています.

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