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Updated: Sep 24, 2025

DNA Sequence Recognition by DNA Primase Using High-Throughput Primase Profiling
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Published on: October 8, 2019

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DNAプライマー合成の開始のための分子基礎

Arthur W H Li1, Katerina Zabrady1, Lewis J Bainbridge1

  • 1Genome Damage and Stability Centre, School of Life Sciences, University of Sussex, Brighton, UK.

Nature
|May 4, 2022
PubMed
まとめ

研究者らは,プライマースポリメラーゼ (Prim-Pol) 酵素のプライマー合成メカニズムを解明し,DNA複製を開始するための保存された分子決定因子を明らかにした. この発見は 触媒ドメインだけで ゲノム複製と適応免疫に 欠かせないプライマーを形成できることを示しています

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