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Updated: Mar 23, 2026

ACT1-CUP1 Assays Determine the Substrate-Specific Sensitivities of Spliceosomal Mutants in Budding Yeast
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ACT1-CUP1 Assays Determine the Substrate-Specific Sensitivities of Spliceosomal Mutants in Budding Yeast

Published on: June 30, 2022

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イーストにおけるmRNAスプライシングの際にTACTAACボックスの認識には,U2型snRNAへの塩基配列が含まれる

R Parker, P G Siliciano, C Guthrie

    Cell
    |April 24, 1987
    PubMed
    まとめ

    イーストU2のsnRNAアナログは,イントロンの保存されたUACUAACボックスを特異的に認識します. この相互作用は,プレ-mRNAスプライシングに不可欠であり,ワトソン・クリックの塩基配列に依存しており,アレル固有の抑制実験によって実証されています.

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